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sequence_alignment [2014/11/13 16:05]
sebastien.renaut created
sequence_alignment [2014/11/17 13:27] (current)
sebastien.renaut
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 === Sequence Alignments === === Sequence Alignments ===
-muscle + 
-mafft +  *[[http://​www.ebi.ac.uk/​Tools/​msa/​muscle/|MUSCLE]]. Multiple Sequence Alignment. Also has a nice web interface to submit jobs directly online 
-t-coffee +  ​*[[http://​mafft.cbrc.jp/​alignment/​software/​|MAFFT]]. Multiple Sequence Alignment program for unix-like operating systems. Alternative to MUSCLE 
-proprietary +  ​*[[http://​www.tcoffee.org/​Projects/​tcoffee/​|t-coffee]]. Multiple Sequence Alignment. Alternative to MUSCLE 
-MEGA+  ​*[[http://​www.ebi.ac.uk/​Tools/​msa/​clustalw2/​|clustalW2]]. Multiple Sequence Alignment. Alternative to MUSCLE 
 +  ​*[[http://​www.megasoftware.net/​|MEGA]]. integrated tool for conducting sequence alignment, inferring phylogenetic trees, estimating divergence time. Fantastic GUI. 
 +  *[[http://​www.mbio.ncsu.edu/​bioedit/​bioedit.html|BioEdit]] Sequence Alignment Editor (for PC only) with various molecular evolution functions. Nice GUI. Use to be one of the leading program. Outdated (?) and no longer supported. 
 +  *Most proprietary software (Sequencher,​ Geneious, CLC Genomics) will also permit multiple sequence alignments.