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Sanger sequencing was previously the main method for providing sequence data, but it has the disadvantage of being time consuming and expensive when analysing a massive amount of data is planned. A revolution in the sequencing field began with pyrosequencing 1) and there are nowadays (as of 2011) many different platforms available for high throughput sequencing.

High throughput sequencing for genetic diversity studies

A few QCBS members have used one or the other high throughput sequencing methods currently (as of 2011) available. One example, that uses a AFLP-like and a pyrosequencing step with a Genome Sequencer FLX (GS-FLX) System is detailed in a specific page High throughput sequencing at the QCBS of this wiki.